The evacuation of whole cities or even regions is an important problem, as demonstrated by recent events such as evacuation of Houston in the case of Hurricane Rita or the evacuation of coastal cities in the case of Tsunamis. A robust and flexible simulation framework for such large-scale disasters helps to predict the evacuation process. Existing methods are either geared towards smaller problems (e.g. Cellular Automata techniques or methods based on differential equations) or are not microscopic (e.g. methods based on dynamic traffic assignment). This paper presents a technique that is both microscopic and capable to process large problems.BMBF, 03G0666E, Verbundprojekt FW: Last-mile Evacuation; Vorhaben: Evakuierungsanalyse und Verkehrsoptimierung, Evakuierungsplan einer Stadt - Sonderprogramm GEOTECHNOLOGIENBMBF, 03NAPAI4, Transport und Verkehr: Verbundprojekt ADVEST: Adaptive Verkehrssteuerung; Teilprojekt Verkehrsplanung und Verkehrssteuerung in Megacitie