The aim of this report is to conduct a global assessment of marine fisheries and biodiversity conservation in order to identify opportunities for The MacArthur Foundation to address issues relating to marine fisheries and biodiversity conservation. By looking at 19 Large Marine Ecosystems Currents in five mega-regions of the world – Africa, South and Southeast Asia, Latin America, the Pacific Islands, and the Polar Regions – the report identifies high-priority current and future challenges and changes facing marine fisheries in each of these megaregions. The report also provides 14 case studies illustrating highly successful solutions strategies and approaches that have proven effective in practice. Two global matrices – one identifying organizations and funders working in the regions, and one identifying 56 successful cases in the marine fisheries sector – are provided to further inform the Foundation as it considers where opportunity and capacity exists for leveraging future support