Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize treatment for our patients.This article will:∙review strategies to measure ADHD symptoms and functional difficulties while seeking to achieve full symptomatic remission throughout the day∙summarize recent findings regarding the management and prioritization of ADHD and comorbid conditions and∙discuss the various pharmacologic treatment options with a focus on recently developed molecules and novel delivery systems</jats:p