Ankle braces effectively limit harmful ankle motions, but may produce hazardous alterations in knee biomechanics. This study determined how four ankle braces (ankle roll guard (ARG), lace-up brace, non-elastic tape, control) impact knee biomechanics during a single-leg cut, and whether the impact differs between sexes. With the lace-up brace, females increased peak abduction angle 2.5º compared to control (p=0.008), whereas, males decreased peak internal rotation moment compared to control (p=0.006) and tape (p=0.002) conditions. During the cut, males exhibited greater knee internal rotation compared to females (p=0.010), but only with ARG (p=0.009), tape (p=0.005), and control (p=0.002) conditions
