Abadie J

BENAZZI, CINZIA

Castagnaro M

Diez L

Gama A

Gartner F

Goldschmidt M

Hellmen E

Kiupel M

Martin de las Mulas J.

Millan Y

Miller M

Nguyen F

Pena L

POLI, ALESSANDRO

SARLI PROF., GIUSEPPE

Zappulli V

English

Archivio della Ricerca - Università di Pisa

31st Meeting of the Europea n Society of Veterinary Pathology and the Europea n College of Veterinary Pathologists -ILa 4th - 7th September 2013 Programme The lnstitute of Education University of London London, UK O Royal > Veterìnary a:: ~~~~~~! W~l 66: Oral Presentations Session D: lnfectious, Wildlife & Neoplastic Disease CONSENSUS PROPOSAL ON ESSENTIAL PHENOTYPE MARKERS ANO HORMONE RECEPTOR ASSESSMENT IN CANINE MAMMARY TUMORS. L Peiia1, A.Gama2, M. Goldschmide, J. Abadie4, C. Benazzi 5, M. Castagnaro6, L.Dfez\ F. Gartner7, E. Hellmen8, M. Kiupel 9, V. Millan10, M. Miller11, F. Nguyen4, A. Poli12, G. Sarli5, V. Zappulli6, J. Martin de las Mulas10 1 Complutense University of Madrid. Spain. 2 University of Tr6s-os-Montes and Alto Douro, Vi/a Rea/, Portuga/. 3 University of Pennsylvania, Philadelphia, USA. 4 LUNAM University, Nantes, France. 5 University of Bologna, ltaly 6 University of Padua, ltaly 7 University of Porto, Portugal 8 Swedish University of Agricultural Sciences, Uppsala, Sweden. 9 Michigan State University, East Lansing, MI, USA 10 University of C6rdoba, Spain. 11 Purdue University, West Lafayette, Indiana, USA. 12 University of Pisa, ltaly laurape@vet.ucm.es lntroduction: lmmunohistochemistry {IHC) has played an increasing role as a diagnostic tool for the identification of neoplasms and pathogens. In dogs with mammary tumors {CMTs), there have been an increasing number of studies looking for reliable diagnostic and/or prognostic immunohistochemical biomarkers but no consensus has been reached. These studies cannot be comp'ared because of the differences in how these biomarkers have been used and evaluated. Materials and Methods: Review of the literature including IHC markers on CMTs in order to detect the best immunolabeling and evaluation systems for each marker. Results: After the review process, the authors reached a consensus regarding practical questions related to the methodology and provide guidelines on immunolabeling for CMTs markers along with the specific recommendations for interpretation of the results for each of these biomarkers in CMTs. Conclusion: By standardizing the methods used for labeling and interpretation of these IHC markers, we aim to ensure consistency an d reproducibility of future study results. 

Consensus proposal on essential phenotype markers and hormone receptor assessment in canine mammary tumors

https://arpi.unipi.it/bitstream/11568/247539/1/Consensus%20proposal%20CMT.pdf

Consensus proposal on essential phenotype markers and hormone receptor assessment in canine mammary tumors

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Archivio della Ricerca - Università di Pisa