Cataloged from PDF version of article.Thesis (M.S.): Bilkent University, Department of Mechanical, İhsan Doğramacı Bilkent University, 2018.Includes bibliographical references (leaves 75-79).It is crucial to engineer novel detection schemes that can extract information
pertinent to the morphological properties of the analytes for widespread usage of
lab-on-a-chip technology. Within the scope of this thesis, a novel method that
is originated in mechanical domain based on NEMS resonators is adapted to
electromagnetic domain with employment of electromagnetic resonators operate
in microwave regime. The viability of the proposed method is assessed both
by experiments and simulations. The designed micro
uidic channel embedded
microstrip resonator is driven at its rst two resonant modes simultaneously by a
phase-locked loop to detect the analyte passage events within the channel. The
attained resolution is 2x108 for both modes at the response time in terms of allan
deviation. With the detection scheme we constructed, the location and electrical
volume of the microdroplets and cells are obtained. It is shown that the two-mode
detection scheme based on microwave resonators can be extended to applications
that exploits even higher-order modes to obtain the size, orientation, skewness
and permittivity information of the target analytes. Morevover, the framework
presented here forms a base for a novel imaging application that can be alternative
to optical microscopy.by Mehmet Kelleci.M.S