Agurto, C

Benites, C

Castillo, N

Hidalgo, JA

English

PubMed

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POSTER PRESENTATION Open Access
Five-year outcomes of HAART at a non-
governmental treatment center in Lima, Peru
N Castillo, C Agurto, C Benites, JA Hidalgo*
From Tenth International Congress on Drug Therapy in HIV Infection
Glasgow, UK. 7-11 November 2010
Background
Ministry of Health in Peru launched an HIV treatment
program with the initial support of the Global Fund in
2004. A few months later, our institution, an NGO work-
ing in HIV prevention, entered the treatment program in
order to contribute to the national efforts to improve
access to HIV care. There are no other available reports
on long-term results of HAART in our country.
Methods
Retrospective medical records review of 149 consecutive
patients that initiated HIV treatment through the
national program at our outpatient Clinic between
February and July 2005. Main clinical and laboratory
outcomes were recorded and reported.
Results
After an observation period of five years, 127 (85.2%) per-
sons continue their care at our Clinic. Mean baseline age
was 34.6 yrs. The group included 34 women (22.8%).
Eight patients died (5.3%), 7 (4.7%) patients were referred
to other centers at their request, and 7 (4.7%) were lost
to follow up. Eighty-five patients (57.0%) were treatment
naive at the moment of joining our treatment program.
One hundred sixteen patients show current virological
success (HIV VL<400 c/ml), with an ITT success rate of
77.8%, and an “on treatment” success rate of 89.7%.
Ninety-five persons have shown sustained virological suc-
cess over the 5 years (89 on NNRTI-based regimens).
Mean baseline CD4 cell count at the moment of treat-
ment initiation was 86/µL. Mean CD4 cell count at five
years follow up is 254/µL. Forty-five patients have
required change of a drug due to an adverse event (most
commonly during the initial months of therapy). Causes
of mortality were opportunistic infections related to IRIS
or previously active (TB, PCP, disseminated histoplasmo-
sis) and 2 cases of NHL. All deaths occurred within then
initial year of treatment. Significant morbidities such as
cancer or TB after the first year of treatment occurred in
8 patients (5.3%). No cardiovascular event has been
observed in this cohort so far.
Conclusions
Outcomes observed at 5 years of HAART are compar-
able to the ones observed in other treatment programs
developed in limited resource settings. The model of
care supported by our NGO is highly successful with no
additional support from public funding other than medi-
cations and monitoring laboratories.
Published: 8 November 2010
doi:10.1186/1758-2652-13-S4-P173
Cite this article as: Castillo et al.: Five-year outcomes of HAART at a
non-governmental treatment center in Lima, Peru. Journal of the
International AIDS Society 2010 13(Suppl 4):P173.
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Castillo et al. Journal of the International AIDS Society 2010, 13(Suppl 4):P173
http://www.jiasociety.org/content/13/S4/P173
© 2010 Hidalgo et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons
Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in
any medium, provided the original work is properly cited.


Five-year outcomes of HAART at a non-governmental treatment center in Lima, Peru

N Castillo

C Agurto

C Benites

JA Hidalgo

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Journal of the International AIDS Society

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Five-year outcomes of HAART at a non-governmental treatment center in Lima, Peru

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