Durighel, Giuliana

Finnemore, Anna E

Groves, Alan M

Hajnal, Jo V

Price, Anthony N

English

PubMed

Hajnal Jo V

Durighel Giuliana

Price Anthony N

Finnemore Anna E

Groves Alan M

Directory of Open Access Journals

Journal of Cardiovascular Magnetic Resonance

Impact of neonatal cardiac receive-array coil on SNR and CNR in newborn infants

Anna E Finnemore

Anthony N Price

Giuliana Durighel

Jo V Hajnal

Alan M Groves

Crossref

Springer - Publisher Connector

POSTER PRESENTATION Open Access
Impact of neonatal cardiac receive-array coil on
SNR and CNR in newborn infants
Anna E Finnemore*, Anthony N Price, Giuliana Durighel, Jo V Hajnal, Alan M Groves
From 2011 SCMR/Euro CMR Joint Scientific Sessions
Nice, France. 3-6 February 2011
Objective
To compare signal to noise ratio (SNR) and contrast to
noise ratio (CNR) for myocardium and blood during
cardiac MR imaging in the newborn using 2 different
receive-array coils. Paediatric Body/Cardiac (Paed-Body)
and Flex-M coils were compared under a clinical inves-
tigation agreement with Philips.
Background
CMR assessments of cardiac function at 3.0 Tesla have
been shown to provide more complete data with greater
reproducibility than existing echocardiographic methods
in newborns [1]. However signal to noise is at a pre-
mium in preterm infants. Further advances in image
quality and spatial resolution are dependent on maxi-
mizing available signal. Prior neonatal CMR imaging has
been performed using a 2-channel Flex-M receiver coil.
However an 8-channel coil for neonatal imaging at 3T
is now available.
Methods
Cardiac MRI scans from 38 newborns of corrected
gestation 26-41 weeks were retrospectively analysed in 2
weight-matched groups. All scans were performed in a
Philips 3T MRI Scanner. Cine images were acquired
with resolution 1.5/1.5/5mm. In 19 infants a 2-channel
Flex-M coil was placed above and below the chest; in 19
an 8-channel Paed-Body receive-array coil was placed
around the infant. Myocardial and blood signal intensity
(SI) were measured at the intraventricular septum and
left ventricular cavity respectively, at end-diastole from
the mid-ventricular level of a short axis stack(Figure 1).
Noise was taken as the mean of three measures of stan-
dard deviation in air surrounding the infant. SENSE and
CLEAR techniques were not used. Images were analysed
offline(CMR tools, CISL, London). SNR was taken as
SI/noise. CNR was taken as (SIblood-SImyocardium)/noise.
Results
The 2 groups of infants were matched for weight
(1923vs1911 grams, p=0.96). The Paed-Body coil pro-
duced significantly higher SNR in myocardium
(101.4vs56.6, p=0.0003), SNR in blood (221.2vs139.9
p=0.003) and CNR (119.8vs83.5 p=0.03) (Figure 2).
These findings persisted when only infants with weight
<2000grams were assessed (myocardial SNR 114.2vs53.7
p=0.002, blood SNR 240.8vs131.1 p=0.01, CNR
126.6vs77.4 p=0.05).
Conclusions
The Paed-Body receive-array coil produces significant
increases in SNR and CNR when performing cardiac
Imperial College, London, UK
Figure 1 Location of measures of signal and background noise
from a short axis image in a newborn infant.
Finnemore et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):P215
http://jcmr-online.com/content/13/S1/P215
© 2011 Finnemore et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.
MR imaging in newborn infants including those weigh-
ing less than 2000g.
Published: 2 February 2011
Reference
1. Groves, et al: Arch Dis Child Fetal Neonatal Ed .
doi:10.1186/1532-429X-13-S1-P215
Cite this article as: Finnemore et al.: Impact of neonatal cardiac receive-
array coil on SNR and CNR in newborn infants. Journal of Cardiovascular
Magnetic Resonance 2011 13(Suppl 1):P215.
Submit your next manuscript to BioMed Central
and take full advantage of: 
• Convenient online submission
• Thorough peer review
• No space constraints or color figure charges
• Immediate publication on acceptance
• Inclusion in PubMed, CAS, Scopus and Google Scholar
• Research which is freely available for redistribution
Submit your manuscript at 
www.biomedcentral.com/submit
Figure 2 Comparison of myocardial and blood SNR and CNR using Paed-Body and Flex-M coils in 38 newborn infants.
Finnemore et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):P215
http://jcmr-online.com/content/13/S1/P215
Page 2 of 2


Arch Dis Child Fetal Neonatal Ed . doi:10.1186/1532-429X-13-S1-P215 Cite this article as: Finnemore et al.: Impact of neonatal cardiac receivearray coil on SNR and CNR in newborn infants.

file:///data/remote/core/dit/data/Springer-OA/pdf/da2/aHR0cDovL2xpbmsuc3ByaW5nZXIuY29tLzEwLjExODYvMTUzMi00MjlYLTEzLVMxLVAyMTUucGRm.pdf

Impact of neonatal cardiac receive-array coil on SNR and CNR in newborn infants

Abstract

Similar works

Full text

Available Versions

Directory of Open Access Journals

Crossref

Springer - Publisher Connector

Springer - Publisher Connector