2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Cao, J

Li, H

Li, L

Shao, SY

Tong, KY

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe

PolyU Institutional Repository

文章编号:1000-5404(2007)19-1855-04 ??????????????????????????曹　军 1 ,邵时云 2 ,李　辉2 ,李　乐 3 , Tong Kaiyu3　　(1?????????????? , ?? 710032;2??????????????? , ?? 710049;3???????????????)　　?　?:目的　???????????????????(ENG)??? , ???????????。方法　????????????? cu ff?? , ?????????。?????????????????? ENG???? ,????????????????。结果　??????????????????? ENG, ?? 、?????? , ??????????? ,????????????????? , ??????????? , ???????????????;????????????? , ????????????????????。结论　????? ENG???????????????。　　???:cuff??;???;????;?????　　??????:R-322;R322. 91;R338. 8　　　 ?????:AO rb icular is oculimuscle activities by ana lyz ing dog’ s e lectroneurogramCAO Jun1 , SHAO Sh i-yun2 , LIHui2 , LI Le3 , TONG Kai-yu3(1Department o fO rthodontics, Q indu S tom ato logy Co llege, FourthM ilitaryM ed ica l Un ive rsity, Xi’ an 710032;2Biomedica l Eng ineering Institute, Xi’ an Jiao tong University, X i’ an 710049;3Depa rtm ent ofH ealth Techno logy and Inform a tics, H ong Kong Po ly technic Unive rsity, Hong Kong, Ch ina)　　Abstract:Object ive　Tomonitor the activ ities of o rbicu laris ocu li muscle by analyzing the electroneu ro-gram (ENG) o f its innervating ne rve. Methods　The ENG was recorded in vivo by a cuff e lectrode imp lantedaround a dog’ s zygomatic b ranch of facia l nerve. The differences between the ENG du ring re lax ing period o f theorbicu la ris oculimusc le and during the constricting pe riod we re ana lyzed to explore aw ay to monitor the muscleactivities. Results　The ENG signa ls ind ica ting occurrences of eye blinking even tsw ere ex tracted in the study.T ime-frequency analysis showed that therew as no ENG differencew hen the orbicu laris ocu limusc le w as in re la-xing periods no mater whe ther it w as in the na tu re eye-opening period or in the interval o f eye blinking. TheENG of orbicularis oculimuscle in constric ting pe riod was different from the ENG in re laxing pe riod at amp litudeand frequency. Conc lus ion　 It is feasib le to monitor the orbicu laris ocu li musc le ac tiv ities by ENG ana lysis.　　Key words:cuff e lectrode;facial nerve;orbicu laris oculimusc le;e lec troneurogram　　?????????????????? ,?????????????????? 、?? ,?????????? ,????????????[ 1] 。?????????????????? ,????????????????????? ,???????　　????:????????(60371025)　　　 　　　Supported by theN ationalNa tural Science Founda tion of China(60371025)　　????:?　?(1968 -),? ,????????? ,????? ,??? ,???????????????????????????。??:(029)84776135, E-mai l:wykun@ fmmu. edu. cn　　????:2007-04-19;????:2007-07-02??????? ,????????? [ 2] 。??????????? ,? cu ff????????????????? , ???????????????(e lectroneurogram , ENG),??????????????????? ,???????????????? ,????????? 。1　?????1. 1　狗面神经颧支神经信号的提取方法1. 1. 1　 cuff?????　　 cuff????????? 、?? ,????? 1,?????????????? , ????? 3?????? , ??????????? 5 mm。?????1855? 29?? 19?2007? 10? 　　?　?　?　?　?　?　?　?ACTA　ACADEM IAE　MED IC INAE　M IL ITARIS　TERTIAE　　Vo .l 29, No. 19Oc.t 2007DOI牶牨牥牣牨牰牥牨牰牤j牣牨牥牥牥牠牭牬牥牬牣牪牥牥牱牣牨牴牣牥牫牬????????????????????? ,?????? 3 mm。? 1　 cuff????????1. 1. 2　 cu ff???????　　??? 、????? , ????? cuff????? 1????????(????? 15 kg)??????????。??????:???????????????????????? ,??????????????? 25 mm , ????????????。????? ,?????? 2. 0 mm。 ?? , ???? 3 mm ??? cuff?? , ????????????????? 1. 4? , ????????。???????? , ????????????????。?????? , ????????????? , ????????? , ???????。1. 2　神经电信号的提取方法1. 2. 1　?????????????????　　 cuff?????????????????????? ,????????????????????????? , ?????????????? [ 3] 。???????????? (SR560,S tandfo rd Research Sy stem s Inc, CA), ????? 50 000, ??? 1 ～ 3 kH z。?????????????。?????????????????。 ???????? ENG???20 kH z????? , ?? 8855????? (H ioki E. E Co rp. ,Japan)?????????? , ????????。??????? , ?????? ENG????? 500 H z????? ,???????????????? 500 H z?。1. 2. 2　?????????????????　　????? 14 d? ,???????????? 2?????????????????。???????? , ???????? ,??????????。　　??????????????????:????????????????? ,????????????????????? , ??????????? , ??????????????。　　???????????????????:????????????????????。 ?????????????????????????????。1. 3　眼轮匝肌处于不同功能状态时 ,狗面神经颧支神经电信号差异性分析　　???????????????????????????????????????????? ,???????? 10??????? ,??????????????????? ,????????? 5 000?????? 、0. 25 s???? ,???????????? RM S、MPF????????。1. 4　统计学分析　　?????? 、?????????????? 3???????? RM S、M PF???????????? ,??????????? Sche ffe??(????)? Dunnett t?? (?????)。?? SPSS 11. 0????。2　??2. 1　自然睁眼状态下 ,狗面神经颧支神经电信号及其频谱特征　　? 2A?????????????????????。?????????????????? , ? 2B????????????。? 2　??????????????????2. 2　有眨眼动作发生时 ,狗面神经颧支神经电信号及其频谱特征　　? 3????????????????????? ,???????????????? ,?????。??????????????? , ENG??????????????????????????。1856 　　　　　　　　　　　? 　? 　? 　? 　? 　? 　? 　? 　　　　　　　　　　　　? 29?? 19?　 ?　? , ?.????????????????????????　　　?? 3???????????? , ???????????????? , ? 4A????????? , ? 4B???????????。?????? , ? 4?? ENG?????????????????。? 3　???????????????????? 4　??????????????????　　?????? 3??????????????????,? 5A????????? ,? 5B???????????。2. 3　眼轮匝肌处于不同功能状态时 ,狗面神经颧支神经电信号差异性分析　　? 1???????????? ,?????? 10?????? 、?????????????????? RMS、M PF????????????。? 5　???????????????????? 1　????????????? ENG??? RM S、MPF?(n=10,  x±s)?? RM S(×10 - 4μV) MPF(H z)?????? 2 758. 7±151. 4 2 706. 5±96. 2?????? 2 734. 3±191. 1 2 691. 5±296. 4??????? 5 132. 4±857. 1ab 2 254. 5±269. 3aba:P <0. 01,与自然睁眼状态比较;b:P <0. 01,与眨眼动作间期比较3　??3. 1　关于神经电信号的提取　　????????? ,?????????????????。???? ,??????????????? ,???????????????????? ,??????????????? ,????????????????????????? [ 4] 。Ho ffe r? S tein??????? , ????? cuff?? ,?????????????????????????。?????????? ,??????????? ,???????????????????? ,????????????????。???? ,?????????????????? (??????????? )[ 5 - 7] ,????????????? ,??????? phe rnic??????????1857? ,??????????????? 。?????????????????????? (?? )????? 、?????????????????????????? [ 8 - 10] 。　　??????????????????????? 、?????? ,????????????????????? ,??????????????? ,?? 3?? ,???????????? ENG??。?????? ,?????????????????? ,?? ,???????? ENG??????????????????????????? 。3. 2　关于狗眼轮匝肌不同功能状态在面神经颧支神经信号上的反应　　????? ,?????????????????????????? 。??????????????????? ,??????????????? ,????????? ,?????????? ,????????????? 。?????????? ,?????????????? ,?????? ,???????????????????? 、?????????????????。????????? ,???????????????????? 、?????????????????????? ,?? 2、4?? ,????? RMS、MPF????????? ,?? 1?? ,????????????????????????。????????? ,???????????? ,?????????????? 、??????????? ,????????????? ,???????? ,?????????????????? 、??????????? ,??????????????????????????????????? 。????????????????????? ,??????????????????????????? ,???????????????? ,?? 4、5?????????????????????? ,???????????????????? ,?? 1???????????????? ,???????????? RMS???? , MPF??????????。??????????????????????????????????? ,????????????????????? ,?????????????????? 、??????????? ,????????????????????????????。????:[ 1] Rahm an I, S adiq SA. Ophthalm icm anagem en t of facial nerve p alsy:areview [ J] . Su rv Oph thalm ol, 2007, 52(2):121 - 144.[ 2] V anderW erf F, Reits D, Sm it A E, et a l. B link recovery in patien tsw ith Be ll’ s palsy: a neurophysiological and behavioral longitud in alstudy[ J] . InvestOph tha lmo lV is S ci, 2007, 48(1):203 - 213.[ 3] Sw eeney JD , K sien sk iD A, M ortim er J T. A nerve cu ff techn ique forselective excitation of periph eral nerve trunk reg ion s[ J] . IEEE T ransB iom ed Eng, 1990, 37(7):706 - 715.[ 4] N ikolic ZM , PopovicD B, S tein R B, et al. In strum entation for ENGand EMG recordings in FES sys tem s[ J] . IEEE Trans B iom ed E ng,1994, 41(7):703 - 706.[ 5] Rozm an J, Zorko B, Selisk ar A, et a l. S elective record ing of neu ro-electric act ivity f rom the periphera l nerve[ J] . P flugers A rch, 2000,440(5 Supp l):R157 -R159.[ 6] Donald son-Nde D, Zhou L, Perk ins T A, et a l. Im p lan tab le telem eterfor long-term electroneurog raphic recordings in an im als and hum ans[ J] . 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IEEE TransRehabi lEng, 1999, 7(2):215 -227.(编辑　薛国文)???????? mmHg???　　根据国家质量技术监督局和卫生部联合发出的质技监局量函 [ 1998]《关于血压计量单位使用规定的补充通知》的精神 ,血压计量单位恢复使用毫米汞柱(mmHg),但首次使用时应注明 mmHg与千帕 [斯卡 ] (kPa)的换算系数(1mmHg=0. 133 kPa)。本刊编辑部1858 　　　　　　　　　　　? 　? 　? 　? 　? 　? 　? 　? 　　　　　　　　　　　　? 29?

Orbicularis oculi muscle activities by analyzing dog’s electroneurogram

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