Microcystic adnexal carcinoma is a rare, locally aggressive neoplasm with both eccrine and follicular differentiation and a high probability
of perineural invasion of the centrofacial region. Given the histopathological features of this tumour, early diagnosis is essential for
adequate management. This report refers to a case of microcystic adnexal carcinoma of the nasogenial region, with infiltration of the deep
planes extending to the anterior wall of the maxillary sinus. Surgical treatment involved wide demolition of the centrofacial region followed
by reconstruction using four locoregional flaps: an Indian flap and a Mustardé flap were used for cutaneous reconstruction; a septal flap to
support the maxillogenial region; a mucosal flap to separate the nasal cavities