TRAITEMENT DES INFECTIONS URINAIRES PAR LA PIVAMPICILLINE. EVALUATION CLINIQUE ET MICROBIOLOGIQUE

Abstract

Pivampicillin, an ester of ampicillin hydrolyzed after oral administration, was given to 25 elderly patients suffering from urinary tract infections. Daily dosage was 3 x 700 mg. This treatment was well tolerated and gave good clinical results. Antibiotic concentration in serum, obtained 2 and 6 hr after oral administration of 700 mg of pivampicillin (an amount equivalent to 500 mg of ampicillin) averaged respectively 6.1 and 1.5 μg/ml; these levels are two times higher than those produced by ampicillin administered orally at the same dose.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe