In the title compound, [Ca(C18H15N2O3S2)(H2O)4]·2C4H10O, the Ca atom, which lies on an inversion centre, is coordinated octahedrally by four water molecules and two anions of the ketene dithioacetal, the donor atoms of which are the amidic carbonyl O atoms. The central backbone of the ligands (excluding the naphthalene and oxoethyl groups) is essentially planar (r.m.s. deviation 0.035 Å). Intramolecular hydrogen bonds are observed from the NH group to the formally ‘thiolate’ S atom and from one coordinated water to the nitrile group and to the ether O atom. Intermolecular hydrogen bonds from the second independent water molecule to the thiolate S atom and the side-chain oxo group connect the molecules in chains parallel to the a axis