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Low Doses of the Carcinogen Furan Alter Cell Cycle and Apoptosis Gene Expression in Rat Liver Independent of DNA Methylation
Authors
Angela Mally
Barh D
+5 more
European Food Safety Authority
J. Kevin Chipman
NTP (National Toxicology Program)
Sibel Ozden
Tao Chen
Publication date
1 January 2010
Publisher
National Institute of Environmental Health Sciences
Doi
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on
PubMed
Abstract
BACKGROUND: Evidence of potent rodent carcinogenicity via an unclear mechanism suggests that furan in various foods [leading to an intake of up to 3.5 mu g/kg body weight (bw)/day] may present a potential risk to human health
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