In Central Europe the inoculation of soybean (Glycine max (L.) Merr.) with different Bradyrhizobia inoculants has led to unsatisfying nodulation results under low temperature conditions. The aim of this study was to test the capacity of commercially available inoculants under cool growing conditions in Central Europe. In 2011 and 2012 four Bradyrhizobia inoculants were tested on three early soybean varieties in a field trial in Germany. The number of nodules, yield and protein content were assessed. Two years data showed a successful nodulation of Product 4, Product 3 and Product 2 while Product 1 cannot be recommended. Independently of soybean variety, all of the three successful inoculants can be advised regarding grain yield. Protein content and protein yield depend on the combination of inoculants and soybean variety. Over the years Product 4 was the most reliable inoculant