In the title linear coordination polymer, [Zn(C6H4N2O4S3)(H2O)4]n, the ZnII atom is coordinated by four O atoms from four water molecules and two O atoms from two [5-(carboxylatomethylsulfanyl)-1,3,4-thiadiazol-2-ylsulfanyl]acetate units in an octahedral coordination environment. The chains are linked into a three-dimensional supramolecular network via O—H⋯O and O—H⋯N hydrogen bonds