Incidence is high, but the predominant strain does not seem to cause greater illness or death than do other strains

Byrnes

Campbell

Chang

Chayakulkeeree

Chen

Datta

Dromer

Eleni Galanis

Fisher

Fraser

Fyfe

Garcia-Hermoso

Goldman

Hajjeh

Kidd

Kwon-Chung

Laura MacDougall

Lizarazo

MacDougall

Mirza

Mitchell

Mohammad Morshed

Nadrous

Perfect

Santos

Sarah Kidd

Seaton

Sorrell

Speed

Stephen

Thomas

Upton

Emerging Infectious Diseases

English

PubMed

null null

Crossref

Epidemiology of<i>Cryptococcus gattii</i>, British Columbia, Canada, 1999–2007

British Columbia, Canada, has the largest reported population of Cryptococcus gattii–infected persons worldwide. To assess the impact of illness, we retrospectively analyzed demographic and clinical features of reported cases, hospitalizations, and deaths during 1999–2007. A total of 218 cases were reported (average annual incidence 5.8 per million persons). Most persons who sought treatment had respiratory illness (76.6%) or lung cryptococcoma (75.4%). Persons without HIV/AIDS hospitalized with cryptococcosis were more likely than those with HIV/AIDS to be older and admitted for pulmonary cryptococcosis. The 19 (8.7%) persons who died were more likely to be older and to have central nervous system disease and infection from the VGIIb strain. Although incidence in British Columbia is high, the predominant strain (VGIIa) does not seem to cause greater illness or death than do other strains. Further studies are needed to explain host and strain characteristics for regional differences in populations affected and disease outcomes

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Epidemiology of Cryptococcus gattii, British Columbia, Canada, 1999–2007

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