The legal issues involved in technology application are inextricably interwoven with the medical issues. This Comment will first discuss the general principles of the scientific method and then contrast their application to pharmacologic therapy with their application to technologic treatments. Bone marrow transplantation will then be analyzed in depth, illustrating the medical issues that third-party payers consider in coverage decisions. Continuing with the model of bone marrow transplantation, this Comment will conclude with an analysis of legal solutions to the denial of access to medical technology