Tumor and normal interstitial fluid proteomic characterization in breast cancer patients receiving neoadjuvant chemotherapy

Authors
Publication date
1 January 2007
Publisher
Attuale:OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD, ENGLAND, OX2 6DP Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: [email protected], [email protected], INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254

Abstract

Tumor progression is related to the malignant potential of cancer cells and microenvironment. To better define the role of proteins secreted by tumor cells and the effect of neoadjuvant chemotherapy (NACT) in breast cancer (BC), we analyzed the bi-dimensional maps of secreted proteins in Tumor Interstitial Fluid (TIF) and in Normal Interstitial Fluids (NIF) before and after NAC

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