Baaijens, F.P.T.

Bosboom, E.M.H.

Bouten, C.V.C.

Oomens, C.W.J.

Thomassen, S.

English

NARCIS 

Transverse mechanical properties of skeletal muscle

Pure OAI Repository

 Transverse mechanical properties of skeletal muscleCitation for published version (APA):Bosboom, E. M. H., Thomassen, S., Oomens, C. W. J., Bouten, C. V. C., & Baaijens, F. P. T. (1999). Transversemechanical properties of skeletal muscle. Poster session presented at Mate Poster Award 1999 : 4th AnnualPoster Contest.Document status and date:Published: 01/01/1999Document Version:Publisher’s PDF, also known as Version of Record (includes final page, issue and volume numbers)Please check the document version of this publication:• A submitted manuscript is the version of the article upon submission and before peer-review. There can beimportant differences between the submitted version and the official published version of record. Peopleinterested in the research are advised to contact the author for the final version of the publication, or visit theDOI to the publisher's website.• The final author version and the galley proof are versions of the publication after peer review.• The final published version features the final layout of the paper including the volume, issue and pagenumbers.Link to publicationGeneral rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.            • Users may download and print one copy of any publication from the public portal for the purpose of private study or research.            • You may not further distribute the material or use it for any profit-making activity or commercial gain            • You may freely distribute the URL identifying the publication in the public portal.If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license above, pleasefollow below link for the End User Agreement:www.tue.nl/taverneTake down policyIf you believe that this document breaches copyright please contact us at:openaccess@tue.nlproviding details and we will investigate your claim.Download date: 17. Nov. 2023Transverse mechanical properties of skeletal muscleMariëlle Bosboom, Sjaak Thomassen,Cees Oomens, Carlijn Bouten, Frank BaaijensEindhoven University of Technology,Faculty of Mechanical Engineering,Dept. of Materials Technology,P.O. Box 513, 5600 MB Eindhoven, the NetherlandsIntroductionContinuum models to study skeletal musclefunctioning [1, 2] need constitutive equations todescribe the muscle’s passive and active behaviour.A problem in formulating 3D constitutive equations isthe lack of data on transverse mechanical properties.ObjectiveDetermine the passive transverse mechanicalproperties of skeletal muscle.✷ In vitro set-up → pilot for in vivo studies✷ Complete muscle since extraction of testingsamples in vivo is impossibleExperimentTransverse compression of 2 rat TA muscles.✷ Muscles excised preserving the in vivo lengthand kept in Ringers (37 ◦C)✷ Set-upCameraPCLoad cellMuscleSupporting plateIndentor✷ Results0 5 10 15 20 25012345t [s]u [mm]TA 1TA 20 5 10 15 20 250481216t [s]F [N]TA 1TA 2Prescribed displacement Indentation forceFE modelSimulations to assess stress- and strain-distributionsin the muscles during the experiments.✷ Plane strain model of mid-cross section✷ Mesh generated for each muscle✷ Muscle behaviour described with Ogden modelW = µα(λα1 + λα2 + λα3 − 3)extended with viscoelasticityS = (1 − δ) ∂W∂ E+∫ t0δ∂W∂ Ee−(t−ξ)/τ dξ✷ Displacement of indentor prescribed✷ ResultsParameter estimationMaterial parameters µ, α, δ and τ are determined bya least squares fit of calculated indentation force onexperimental data [3].Results✷ Final parameter estimatesµ α δ τSpecimen [kPa] [-] [-] [s]TA muscle 1 13.5 5.0 0.70 2.7TA muscle 2 19.7 4.4 0.74 2.7✷ Comparison measured indentation force andcalculations using the final parameter estimates0 5 10 15 20 250481216t [s]F [N]measured  calculated0 5 10 15 20 250481216t [s]F [N]measured  calculatedTA muscle 1 TA muscle 2ConclusionsThis numerical-experimental approach only requiredindentation force and displacement as input data.Since these can be assessed in an in vivo indentationexperiment, the method is applicable in vivo.References:[1] GIELEN, A.W.J., ET.AL.: Comp. Meth. Biomech. Biomed. Engng. (in press, 1999).[2] VANKAN, W.J., ET.AL.: J. Biomech. (vol. 31, pp. 401-409, 1998).[3] MEUWISSEN, M.H.H., ET.AL.: J. Mater. Process. Technol. (vol. 75, pp. 204-211, 1999).

Bosboom, EMH Mariëlle

Thomassen, S

Oomens, CWJ Cees

Bouten, CVC Carlijn

Baaijens, FPT Frank

Repository TU/e

https://pure.tue.nl/ws/files/3389408/36795358523705.pdf

Transverse mechanical properties of skeletal muscle

Abstract

Similar works

Full text

Available Versions

NARCIS

Pure OAI Repository

Repository TU/e