First 1,3-Dipolar Cycloaddition of Azomethine Ylides With (E)-Ethyl 3-Fluoroacrylate. Regio- and Stereoselective Synthesis of Enantiopure Fluorinated Prolines.

Abstract

Enantiopure fluorinated prolines with four chiral centers were obtained from 1,3-dipolar cycloaddition of azomethine ylides and (E)-ethyl 3-fluoroacrylate

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