objective. To provide an overview of the economic aspects of needlestick and sharps injury (NSI) management among healthcare personnel
(HCP) within a Health Technology Assessment project to evaluate the impact of safety-engineered devices on health care
methods. A systematic review of economic analyses related to NSIs was performed in accordance with the PRISMA statement and by searching
PubMed and Scopus databases (January 1997–February 2015). Mean costs were stratified by study approach (modeling or data driven) and type of
cost (direct or indirect). Costs were evaluated using the CDC operative definition and converted to 2015 International US dollars (Int).results.Atotalof14studieswereretrieved:8data−drivenstudiesand6modelingstudies.Amongthem,11studiesprovideddirectandindirectcostsand3studiesprovidedonlydirectcosts.Themedianofthemeansforaggregate(direct+indirect)costswasInt747 (range, Int199–Int1,691).
The medians of the means for disaggregated costs were Int425(range,Int48–Int1,516)fordirectcosts(9studies)andInt322 (range, Int152–Int413) for indirect costs (6 studies). When compared with data-driven studies, modeling studies had higher disaggregated and aggregated costs, but
data-driven studies showed greater variability. Indirect costs were consistent between studies, mostly referring to lost productivity, while direct costs
varied widely within and between studies according to source infectivity, HCP susceptibility, and post-exposure diagnostic and prophylactic protocols.
Costs of treating infections were not included, and intangible costs could equal those associated with NSI medical evaluations.
conclusions. NSIs generate significant direct, indirect, potential, and intangible costs, possibly increasing over time. Economic efforts
directed at preventing occupational exposures and infections, including provision of safety-engineered devices, may be offset by the savings from
a lower incidence of NSIs