High penetrances of BRCA1 and BRCA2 mutations confirmed in a prospective series

A Antoniou; A Dørum; AB Hill; AC Antoniou; Anita Vabø; B Górski; CB Begg; Christoffer Jonsrud; DF Easton; DG Evans; DG Evans; G Evans; GR Evans; H Meijers-Heijboer; I Hagen Anne; Jaran Apold; K Heimdal; L Mæhle; Lars F Engebretsen; Lovise Mæhle; MC King; Neal Clark; P Moller; P Møller; P Møller; Pål Møller; TL Bodd; Trond Ludvigsen; Z Einbeigi

High penetrances of BRCA1 and BRCA2 mutations confirmed in a prospective series

Authors: A Antoniou
A Dørum
AB Hill
AC Antoniou
Anita Vabø
B Górski
CB Begg
Christoffer Jonsrud
DF Easton
DG Evans
DG Evans
G Evans
GR Evans
H Meijers-Heijboer
I Hagen Anne
Jaran Apold
K Heimdal
L Mæhle
Lars F Engebretsen
Lovise Mæhle
MC King
Neal Clark
P Moller
P Møller
P Møller
Pål Møller
TL Bodd
Trond Ludvigsen
Z Einbeigi
Publication date: 1 January 2010
Publisher: BioMed Central
Doi

Abstract

Penetrances of BRCA1 and BRCA2 mutations have been derived from retrospective studies, implying the possibility of ascertainment biases to influence the results

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