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Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study
Authors
Peter C Austin
Minh Duong-Hua
+5 more
Tara Gomes
David N Juurlink
Catherine M Kelly
Lawrence F Paszat
Kathleen I Pritchard
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BMJ Publishing Group Ltd.
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PubMed
Abstract
Objective To characterise whether some selective serotonin reuptake inhibitor (SSRI) antidepressants reduce tamoxifen’s effectiveness by inhibiting its bioactivation by cytochrome P450 2D6 (CYP2D6)
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Last time updated on 02/01/2020