83 patients, 41 male and 42 female, mean age 54,04, operated on of mitro-aortic valve replacement from Jan 1982 to December 1987 were examinated to identify statistically significative operative risk factors. The vast majority of patients had calcific involvement of one (11,4%) or two (48,2%) valves; 7 cases underwent myocardial revascularization for concomitant coronary artery lesions and 17 (20,4%) had previously undergone cardiac operations. The hospital mortality was 8,4%, resulting significantly (p<0.05) influenced by more severe functional class of New Your Heart Association (NYHA) and by involvement of respiratory, renal and hepatic function; incremental risk factors for early mortality
