L1 gene sequence of a putative novel type human papillomavirus in an immunocompetent patient with glans lichen sclerosus

Abstract

6nononeThe identification of a putative novel type human papillomaviruses (HPV) strain related to HPV-RTRX3 in a subject with penile skin warts and glans lichen sclerosus is reported. A beta-HPV-RTRX3-like strain was detected in a immunocompetent patient with glans lichen sclerosus. HPV screening was performed by PCR in L1 gene. The MY fragment showed 99% nt identity with HPV-RTRX3 and 64.5% nt identity with HPV-37. The remaining part of the L1 gene showed similarity with HPV 80, 15, 17, and 37. Based on the presence of penile lichen sclerosus and the HPV-RTRX3-like strain found in our patient, a potential correlation was hypothesized.Paolucci, Stefania; Fiorina, Loretta; Piralla, Antonio; Novati, Stefano; Zerbinati, Nicola; Baldanti, FaustoPaolucci, Stefania; Fiorina, Loretta; Piralla, Antonio; Novati, Stefano; Zerbinati, Nicola; Baldanti, Faust

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