Hyperglycemia and liver glycogenolysis in histamine administered frogs

Abstract

Histamine acid phosphate [51-​74-​1] (0.01 mg, i.m.) administration in frogs caused hyperglycemia, a decrease in the liver glycogen [9005-​79-​2] content, and an increase in the rate of glucose [50-​99-​7] absorption in isolated intestinal segments. Thus, besides acting as a local hormone, histamine also affects carbohydrate metab