Phytotomy (anatomy) is the general term for the study of the internal structure of plants. In this study, anatomical structures of the stem and leaf of taxa viz., Orthosiphon rubicundus Benth., Ocimum basilicum Linn., Leucas cephalotes Spreng., and Coleus forskohlii Briq., belonging to the Lamiaceaewere examined and compared. The studied taxa show some differences and similarities in the stem and leaf shape and structure. Arrangement of epidermis, trichomes, cortex, endodermis, pericycle, vascular bundles types and the presence of collenchyma, palisade and spongy parenchyma layer in the leaf blade. A Macromorphological and micromorphological detail of different parts of the plant body provides information of taxonomical significance