Liquid residue from pig farming contains nutrients that can be used for the fertilization of cultivated soils. The aim of this study was to evaluate chemical and microbiological changes in a sandy soil under pasture with Bermuda Grass (Cynodon spp) that received doses of pig liquid waste (PLW). The experiment was conducted in Cianorte-PR, Brazil , in a Typic Hapludox soil with sandy te xture . The treatments consisted of 30, 60 and 90 m3 ha-1yr-1 of PLW or chemical fertilizer (CF ) applied for two years in a randomized block design, with three replications. Soil samples were taken at 0-10 cm, 10-20 cm and 20-40 cm layers , after three mont hs of the second consecutive application of PLW in the second year, before grazing. PLW increased the concentrations of P, C and K at 10-20 and 20-40 cm soil depth, in addition to increasing the microbial biomass carbon and nitrogen and the population of rhizobia at 0-10-10 cm, in the treatment with 90 m3 ha -1yr-1. PLW improve the chemical fertility at deeper soil layers and the biological fertility at 0 -10 cm of a sandy soil under pasture