Organci-Inorganic Hybrid Silica Monolith Based Covalently Bonded Aptamer Affinity Chromatography Column for Thrombin Detection

Abstract

Aptamers, generally selected by the SELEX(systematic evolution of ligands by exponential) approach, are short(100nt )DNA-or RNA-based oligonucleotides.Aptamers, generally selected by the SELEX(systematic evolution of ligands by exponential) approach, are short(100nt )DNA-or RNA-based oligonucleotides