Helenius, Ilkka

Jalanko, Tuomas

Keskinen, Heli

Koivusalo, Antti

Korhonen, Katariina

Lukkarinen, Heikki

Journal of Children s Orthopaedics

PubMed

Heli Keskinen

Heikki Lukkarinen

Katariina Korhonen

Tuomas Jalanko

Antti Koivusalo

Ilkka Helenius

Springer - Publisher Connector

The lifetime risk of pneumonia in patients with neuromuscular scoliosis at a mean age of 21 years: the role of spinal deformity surgery

Helsingin yliopiston digitaalinen arkisto

The lifetime risk of pneumonia in patients with neuromuscular scoliosis at a mean age of 21 years : the role of spinal deformity surgery

Background Patients with neuromuscular disorders often have an increased risk of pneumonia and decreased lung function, which may further be compromised by scoliosis. Scoliosis surgery may improve pulmonary function in otherwise healthy patients, but no study has evaluated its effect on the risk of pneumonia in patients with neuromuscular scoliosis (NMS). Methods The patient charts of 42 patients (mean age 14.6 years) who had undergone surgery for severe NMS (mean scoliosis 86°) were retrospectively reviewed from birth to a mean of 6.1 years (range 2.8–9.5) after scoliosis surgery. The main outcome was radiographically confirmed pneumonia as a primary cause for hospitalization. We excluded postoperative (3 months) pneumonia from the analyses. Results The lifetime annual incidence of pneumonia was 8.0/100 before and 13.4/100 after scoliosis surgery ( p &gt; 0.10). The mean number of hospital days per year due to pneumonia were 0.59 (SD 2.3) before scoliosis surgery and 2.24 (SD 6.9) after surgery ( p &gt; 0.10). Multivariate analysis demonstrated that lifetime risk factors for pneumonia were epilepsy (RR 15.2, 95 % CI 1.3–176.8, p = 0.027), non-cerebral palsy (CP) etiology (RR = 10.2, 95 % CI 3.2–32.7, p &lt; 0.001) and major scoliosis (main curve &gt;70°; RR = 11.3, 95 % CI 1.8–70.7, p = 0.01). Conclusions Epilepsy, non-CP etiology and major scoliosis are significant risk factors for pneumonia in patients with NMS. Scoliosis surgery does not decrease the incidence of pneumonia in patients with severe NMS. Level of Evidence Retrospective comparative study, Level III. </jats:sec

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The lifetime risk of pneumonia in patients with neuromuscular scoliosis at a mean age of 21 years: The role of spinal deformity surgery

http://dx.doi.org/10.1007/s11832-015-0682-8

The lifetime risk of pneumonia in patients with neuromuscular scoliosis at a mean age of 21 years : the role of spinal deformity surgery

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Helsingin yliopiston digitaalinen arkisto

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