INTRODUCCI
3N: El dengue es en la actualidad la enfermedad viral m\ue1s importante transmitida por mosquitos, con m\ue1s de 2.500 millones de personas expuestas. METODOLOG\ucdA: Para identificar factores de riesgo para shock por dengue, se dise\uf1\uf3 un estudio observacional, anal\uedtico, prospectivo, con 392 ni\uf1os con dengue con criterios de alarma; divididos en dos grupos, 51 que evolucionaron hasta shock; y 341 que no presentaron shock. En el grupo con shock, se registraron los datos en las 24 horas previas a su presentaci\uf3n; en el grupo sin shock, los datos registrados fueron los de mayor alteraci\uf3n durante el per\uedodo cr\uedtico de la enfermedad. RESULTADOS: Mediante regresi\uf3n log\uedstica binaria se identific\uf3 como factores de riesgo para s\uedndrome de shock dengue: infecci\uf3n anterior por dengue [RO: 4,7 IC 95% (2,6 - 8,7) p =3D 0,001], diferencia de presi\uf3n arterial sist\uf3lica menos diast\uf3lica menor de 20 mm de Hg. [RO: 3,1 IC 95% (1,3 - 5,9) p =3D 0,049], hemoconcentraci\uf3n mayor del 20% [RO: 4,1 IC 95% (2,7 - 7,3) p =3D 0,031], y leucocitos mayores de 7.000/mm3 [RO: 3,3 IC 95% (2,9 - 8,1) p =3D 0,037]. CONCLUSION: La atenci\uf3n a la diferencia entre tensi\uf3n arterial sist\uf3lica y diast\uf3lica, la hemoconcentraci\uf3n, y el recuento leucocitario, con antecedente de infecci\uf3n anterior por dengue, debe alertar al m\ue9dico sobre el alto riesgo para s\uedndrome de shock por dengue.PALABRAS CLAVES DEL AUTOR:
Dengue. Shock. Factores de riesgo
ABSTRACTDENGUE SHOCK: RISK FACTORS
INTRODUCTION: Dengue is currently the most important viral disease transmitted by mosquitoes, with more than 2,500 million people exposed. METHODOLOGY: To identify risk factors associated with dengue shock, we designed an observational, analytical, prospective study, with 392 children with dengue and alarm criteria, divided into two groups, 51 who progressed to shock, and 341 who did not have shock. In the shock group, data were recorded in the 24 hours before presentation of shock, in the group without shock, the recorded data were the most affected during the critical period of the disease. RESULTS: Through Binary logistic regression was identified as risk factors for dengue shock syndrome: previous dengue infection [OR: 4.7 95% CI (2.6 - 8.7) p =3D 0.001], difference of systolic minus diastolic blood pressure below 20 mm Hg. [OR: 3.1 95% CI (1.3 - 5.9 ) p =3D 0.049], hemoconcentration more than 20% [OR: 4.1 95% CI (2.7 - 7.3) p =3D 0.031], and leukocytes over 7.000/mm3 [OR: 3.3 95% CI (2.9 - 8.1) p =3D 0.037]. CONCLUSION: Attention to the difference between systolic and diastolic blood pressure, hemoconcentration, and the leukocyte count, with a previous history of dengue infection, should alert the clinician to the high risk for dengue shock syndrome.KEY WORDS: Dengue. Shock. Risk Factors. <br
