PERFIL CL\ucdNICO-EPIDEMIOLOGICO DEL S\ucdNDROME DE LIPODISTROFIA EN PACIENTES CON VIH/SIDA

Abstract

Se realiz\uf3 una investigaci\uf3n descriptiva, transversal, para establecer el perfil cl\uednico-epidemiol\uf3gico del S\uedndrome de Lipodistrofia (SLD) en pacientes con VIH/SIDA. La poblaci\uf3n estuvo constituida por 80 pacientes seropositivos, que asistieron a la consulta de SIDA/ITS del Hospital Universitario "Dr. Miguel Ora\ue1" de Guanare, de estos, conformaron la muestra 58, diagnosticados previamente con SDL y cumplieron con los criterios de inclusi\uf3n y exclusi\uf3n del estudio. Los datos fueron obtenidos de fuente primaria, directamente de los pacientes y fuente secundaria de las historias cl\uednicas. Se encontr\uf3 que la edad present\uf3 una variaci\uf3n 38,4 +- 12,5 a\uf1os, Los h\ue1bitos alcoh\uf3licos (44,8%) y h\ue1bitos tab\ue1quicos e hipertensi\uf3n arterial (41,4%) son los antecedentes familiares m\ue1s relevantes. El tiempo de diagn\uf3stico de VIH/SIDA y tratamiento antirretroviral combinado fue =3D 4 a\uf1os en 56,6% de los pacientes; m\ue1s de la mitad (52,2%) tienen un tiempo de uso menor o igual a 3 a\uf1os; s\uf3lo 10,9% ha utilizado antirretrovirales entre 10 y 15 a\uf1os. Del total de pacientes con \uedndice de masa corporal normal, 61,3% present\uf3 s\uedndrome ginecoide. Las alteraciones en cara-mejilla, tr\uedceps y b\uedceps se diagnosticaron en mayor porcentaje en hombres que en mujeres, no obstante, en estas \ufaltimas, fue predominante el aumento del per\uedmetro abdominal. El perfil lip\ueddico mostr\uf3, niveles de colesterol LDL, entre alto-limite y alto; asimismo, niveles de triglic\ue9ridos entre elevado-limite y elevado. Los resultados develan que los hallazgos encontrados no son concluyentes, sin embargo, orientan al m\ue9dico para la revisi\uf3n de pautas en el tratamiento, actividades de prevenci\uf3n y control del paciente. PALABRAS CLAVE: Lipodistrofia. VIH/SIDA. Terapia Antirretroviral. CLINICAL AND EPIDEMIOLOGICAL PROFILE LIPODYSTROPHY SYNDROME IN HIV/AIDS KEY WORDS: Lipodistrofia. HIV/AIDS. Anti-retroviral Therapy. ABSTRAC There was realized a descriptive, transverse investigation, to establish the clinical - epidemiological profile of Lipodistrofia's Syndrome (SLD) in patients with HIV/AIDS. The population was constituted by 80 seropositive patients, who were present at SIDA/ITS's consultation of the University Hospital Guanare's "Dr. Michael Ora\ue1", of these, 58 shaped the sample, diagnosed before with SDL and expired with the criteria of incorporation and exclusion of the study The information was obtained of primary source, directly of the patients and secondary source of the clinical histories. One thought that the age presented a variation 38,4 +- 12,5 years, The alcoholic habits (44,8%) and habits tab\ue1quicos and arterial hypertension (41,4%) they are the most relevant familiar precedents. The time of diagnosis of HIV/AIDS and anti-retroviral combined treatment was =3D 4 years in 56,6% of the patients; more than the half (52,2%) they have a time of minor or equal use to 3 years; only 10,9% has used anti-retroviral drugs between 10 and 15 years. Of the total of patients with index of corporal normal mass, 61,3% presented syndrome ginecoide. The alterations in face - cheek, triceps and biceps were diagnosed in major percentage in men that in women, nevertheless, in the above mentioned, there was predominant the increase of the abdominal perimeter. The profile lip\ueddico showed, levels of cholesterol LDL, between high place - limit and high place; likewise, level of triglic\ue9ridos between high limit and raised. The results develan that the opposing findings are not conclusive, nevertheless, orientate the doctor for the review of guidelines in the treatment, activities of prevention and control of the patient