Atkinson, SH

Cox, SE

Doherty, C

Fulford, T

Ghattas, H

Kwiatkowski, D

Nweneka, CV

Prentice, A

Rockett, K

English

LSHTM Research Online

A base substitution in the promoter associated with the human haptoglobin 2-1 modified phenotype decreases transcriptional activity and responsiveness to interleukin-6 in human hepatoma cells.

A simple salting out procedure for extracting DNA from human nucleated cells.

A-61C and C-101G Hp gene promoter polymorphisms are, respectively, associated with ahaptoglobinaemia and hypohaptoglobinaemia in Ghana.

An immune basis for malaria protection by the sickle cell trait.

Analysis of the affinity of each haptoglobin polymer for hemoglobin by two-dimensional affinity electrophoresis.

Antisporozoite antibodies and immunity to malaria in a rural Gambian population.

Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon.

Association of the haptoglobin phenotype (1-1) with falciparum malaria in Sudan.

Biological and clinical significance of haptoglobin polymorphism in humans.

Difference in hemoglobin-binding ability of polymers among haptoglobin phenotypes.

Distribution of lymphocyte subsets in bone marrow and peripheral blood is associated with haptoglobin type. Binding of haptoglobin to the B-cell lectin CD22.

DNA polymorphisms in the controlling region of the human haptoglobin genes: a molecular explanation for the haptoglobin 2-1 modified phenotype.

Effect of haptoglobin on the metabolism of vitamin C.

Enhanced phagocytosis of ringparasitized mutant erythrocytes: a common mechanism that may explain protection against falciparum malaria in sickle trait and beta-thalassemia trait.

Fribourg-Blanc A

Genetic markers and malaria.

Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease.

Genotyping of the common haptoglobin Hp 1/2 polymorphism based on PCR.

Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria.

Haptoglobin 2-2 phenotype is a risk factor for type 2 diabetes in Ghana.

Haptoglobin and malaria.

Haptoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release.

Haptoglobin gene promoter polymorphism and haplotypes are unique in different populations.

Haptoglobin gene subtyping by restriction enzyme analysis.

Haptoglobin genotype modulates the balance of Th1/Th2 cytokines produced by macrophages exposed to free hemoglobin.

Haptoglobin genotypes are not associated with resistance to severe malaria in The Gambia. Trans R Soc Trop Med Hyg 96:

Haptoglobin genotyping by allele-specific polymerase chain reaction amplification.

Haptoglobin levels are associated with haptoglobin genotype and alpha+ -Thalassemia in a malaria-endemic area.

Haptoglobin phenotype and gestational diabetes.

Haptoglobin phenotype appears to affect the pathogenesis of American trypanosomiasis. Ann Trop Med Parasitol 100: 213–221. 7 .A s l e hR ,G u e t t aJ ,K a l e t - L i t m a nS ,M i l l e r - L o t a nR

Haptoglobin phenotypes and malaria infection in pregnant women at delivery in western Cameroon.

Haptoglobin phenotypes in HIV-1-seropositive patients in Ghana: decreased risk for Hp0 individuals.

Haptoglobin polymorphism and its relationship to malaria infections in The Gambia.

Haptoglobin polymorphism, iron metabolism and mortality in HIV infection.

Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery.

Human serum haptoglobin is toxic to Plasmodium falciparum in vitro.

Hypohaptoglobinaemia as an epidemiological and clinical indicator for malaria. Results of two studies in a hyperendemic region in West Africa.

Identification of haptoglobin as an alternative ligand for CD11b/CD18.

Identification of the haemoglobin scavenger receptor.

Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on Haptoglobin and

Iron, haptoglobin phenotype, and HIV-1 viral load: a cross-sectional study among pregnant Zimbabwean women.

Limited influence of haptoglobin genotypes on severe malaria in Ghanaian children.

Malaria, cause of ahaptoglobinaemia in Africans.

Red blood cell defects and malaria.

Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases.

Simple PCR detection of haptoglobin gene deletion in anhaptoglobinemic patients with antihaptoglobin antibody that causes anaphylactic transfusion reactions.

SNPHAP: a program for estimating frequencies of large haplotypes of SNPs

The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya.

The haptoglobin 2-2 phenotype affects serum markers of iron status in healthy males.

The haptoglobin-gene deletion responsible for anhaptoglobinemia.

The Sickle Cell Trait Is Associated with Enhanced Immunoglobulin G Antibody Responses to Plasmodium falciparum Variant Surface Antigens.

Haptoglobin genotype, haemoglobin and malaria in Gambian children

http://researchonline.lshtm.ac.uk/10175/1/pone.0000362.pdf

Haptoglobin genotype, haemoglobin and malaria in Gambian children

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