Four patients with malignant fibrous histiocytoma of bone (MFH-B) metastasizing to brain are reported. In two cases, signs
of cerebral involvement developed between 4 and 28 months after diagnosis. Both patients had known pulmonary or bony
metastases. As a consequence of this experience, two further patients were subsequently identified, one with a definite
cerebral metastasis and one who had an asymptomatic supratentorial lesion, possibly metastatic. It is suggested that patients
with MFH-B and widespread metastatic disease at presentation or developing within a short interval should undergo
cerebral imaging