Situs inversus totalis is an inherited condition characterized
by a mirror-image transposition of thoracic and abdominal organs. It often coexists
with other anatomical variations. Transposition of the organs imposes special demands
on the diagnostic and surgical skills of the surgeon. We report a case of a 34-year-old
female patient presented with left upper quadrant pain, signs of acute abdomen, and
unknown situs inversus totalis. Severe acute cholecystitis was diagnosed,
and an uneventful laparoscopic cholecystectomy was performed. A posterior cystic
artery was identified and ligated. Laparoscopic cholecystectomy is feasible in patients
with severe acute calculus cholecystitis and situs inversus totalis; however,
the surgeon should be alert of possible anatomic variations