This paper is an exploratory account of the further development and application of a hybrid framework,
StructurANTion, that is based on Structuration Theory and Actor Network Theory (ANT). The use of social
theories in general and their use in information systems (IS) research in particular is explored leading to
the use of the framework to examine the concept of what are termed humanchine networks in the context
of clinical audit, within a healthcare Primary Care Trust (PCT). A particular focus is on the manner in which
information systems-based reflexivity contributes to both entrenching a networks’ structurated order as
well as contributing to its emancipatory change. The case study compares clinic-centric and patientcentric
audit and seeks to further extend the understanding of the role of information and information
systems within structurated humanchine activity systems. Conclusions indicate that the use of more
socially informed IS methods and approaches can incorporate more emancipatory ideals and lead to
greater adoption and usage of more relevant and useful clinical information systems and practices