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Avalos, Berenice

Cabrera, Gustavo

Rangel, Edgar

Segura-Pacheco, Blanca

Velazquez, Dora

English

PubMed

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HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo

Blanca Segura-Pacheco

Berenice Avalos

Edgar Rangel

Dora Velazquez

Gustavo Cabrera

Bergelson JM: a virus receptor within the tight junction. Adv Drug Deliv Rev

Capogrossi MC: Transcriptionally active drugs improve adenovirus vector performance in vitro and in vivo. Gene Ther

CC: Clinical Development of Histone Deacetylase Inhibitors as Anticancer Agents. Annu Rev Pharmacol Toxicol

Curiel DT: Genetic targeting strategies for adenovirus. Mol Pharm

Curiel DT: Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral Transgene Expresion. Cancer Res

Curiel DT: Recombinant adenovirus-mediated gene transfer to genitourinary epithelium in vitro and in vivo. Cancer Gene Ther

Development and application of adenoviral vectors for gene therapy of cancer. Cancer Gene Ther

Dewhurts S: Valproic acid enhances gene expression from viral gene transfer vectors. J Virol Methods

Duenas-Gonzalez A: Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study. Mol Cancer

Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies. Med Res Rev

Finberg RW: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science

Fojo T: Enhanced adenovirus transgene expression in malignant cells treated with the histone deacetylase inhibitor FR901228. Cancer Res

Garver RI Jr: Amplification of recombinant adenoviral transgene products occurs by inhibition of histone deacetylase. Virology

H: Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously. Clin Cancer Res

Heinzel T: Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells.

Histone deacetylase inhibitor FR901228 enhances adenovirus infection of hematopoietic cells. Blood

Hsieh JT: Epigenetic regulation of coxsackie and adenovirus receptor (CAR) gene promoter in urogenital cancer cells. Cancer Res

Hsieh JT: Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy. Cancer Res

Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene. Biochem Biophys Res Commun

Intra-arterial adenoviral mediated tumor transfection in a novel model of cancer gene therapy. Molecular Cancer

McCormick F: Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: potential relevance to gene therapy. Cancer Res

Molecular and cell insights into the coxsackie-adenovirus receptor: Role in cellular interactions in the stem cell niche. Brain Res Rev

O'Malley BW Jr: Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer. Clin Cancer Res

Pelicci PG: Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer

PL: Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle. Mol Ther

PN: Valproic acid alters chromatin structure by regulation of chromatin modulation proteins. Cancer Res

PS: Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.

PS: Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res

RK: Coxsackievirus adenovirus receptor expression predicts the efficiency of adenoviral gene transfer into non-small cell lung cancer xenografts. Clin Cancer Res

SE: Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR90 NSC 630176), in patients with refractory neoplasms.

Strategies to Adapt Adenoviral Vectors for Targeted Delivery.

Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor gene.

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2.

Valproic acid inhibits angiogenesis in vitro and in vivo. Mol Pharmacol

http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.273.9142

HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo

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