To alleviate material limitations of the additive manufacture of tissue scaffolds, researchers have looked to
indirect fabrication approaches. The feature resolution of these processes is limited however, due to the viscous
ceramic slurries that are typically employed. To alleviate these limitations, the authors look to an indirect
fabrication process wherein a pattern, created using Fused Deposition Modeling, is biomimetically mineralized with
an aqueous simulated body fluid, which forms a bonelike hydroxyapatite throughout the scaffold pattern.
Mineralized patters are then heat treated to pyrolyze the pattern and sinter the minerals. With this process, scaffolds
were created with wall thicknesses as small as 150 m and internal channel diameters of 280-340 m, an
appropriate range for bone tissue engineering.Mechanical Engineerin
