The present study investigated the effects of excitation of the dorsolateral prefrontal cortex (DLPFC) with repetitive transcranial magnetic stimulation (rTMS) on deceptive behaviour. The event-related potential (ERP) component P300 is well known as a neural marker of deception. P300 amplitude was examined in response to critical, familiar, and neutral stimuli in a task similar to the concealed information test. The electroencephalography (EEG) of 13 volunteers was recorded combined with rTMS. We did not find a difference in response to rTMS between right and left DLPFC as initially expected. However, TMS elicited a higher mean P300 amplitude to the critical stimulus compared to sham condition. Therefore, noninvasive prefrontal cortex excitation by rTMS can be used to increase the sensitivity of P300 to critical items in an analogue of the concealed information test
