Acupuncture, biofeedback, and S-adenosyl methionine (SAMe) have been shown to have some efficacy in the treatment of fibromyalgia in randomized controlled trials. Spa treatments, hypnotherapy, massage, and meditation may be effective, but they have been evaluated on the basis of less well-designed studies. Bright light treatment, lasers, selenium, chiropractice, musical tones, and malic acid/magnesium are not effective