Abstract from American College of Clinical Pharmacy 2005 Spring Practice and Research Forum/Updates in Therapeutics, Myrtle Beach, SC, April 10-13, 2005

Ash, Jennifer L.

Gervasio, Jane M.

Rodman Jr., George H.

Zaloga, Gary P.

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Butler UniversityDigital Commons @ Butler UniversityScholarship and Professional Work – COPHS College of Pharmacy & Health Sciences3-2005Blood glucose concentration does not correlatewith organ failure or outcome in trauma patientsreceiving enteral nutritionJennifer L. AshButler UniversityJane M. GervasioButler University, jgervasi@butler.eduGary P. ZalogaClarian Health PartnersGeorge H. Rodman Jr.Clarian Health PartnersFollow this and additional works at: http://digitalcommons.butler.edu/cophs_papersPart of the Pharmacy and Pharmaceutical Sciences CommonsThis Article is brought to you for free and open access by the College of Pharmacy & Health Sciences at Digital Commons @ Butler University. It hasbeen accepted for inclusion in Scholarship and Professional Work – COPHS by an authorized administrator of Digital Commons @ Butler University.For more information, please contact fgaede@butler.edu.Recommended CitationAsh, Jennifer L.; Gervasio, Jane M.; Zaloga, Gary P.; and Rodman Jr., George H., "Blood glucose concentration does not correlate withorgan failure or outcome in trauma patients receiving enteral nutrition" (2005). Scholarship and Professional Work – COPHS. Paper 24.http://digitalcommons.butler.edu/cophs_papers/24Blood glucose concentration does not correlate with organ failure or outcome in trauma patients receiving enteral nutrition !Jennifer L. Ash, Jane M. Gervasio, Gary P. Zaloga, George H. Rodman Jr. !!Purpose: The objective of this study was to evaluate the relationship between 1) blood glucose concentrations and outcomes and 2) blood glucose concentrations and nutrient intake in critically ill trauma patients receiving enteral nutrition (EN). !Methods: This study is a retrospective chart review assessing the blood glucose concentrations in 120 adult trauma patients receiving EN during the first 7 days in the ICU. The relationship between blood glucose concentrations and organ function (renal, pulmonary, cardiovascular, central nervous system), ventilator days, amount of calories received, ICU LOS, hospital LOS, and number of infections was evaluated using linear regression. !Results: Patients had a mean age of 43.6 ± 18.1 years; 73.3% patients were male; and 8.3% of the population had a diagnosis of diabetes mellitus prior to admission. Mean blood glucose concentrations versus various outcomes are summarized in the following tables: !Table 1. Blood glucose vs. organ failure Outcome Renal failure Respiratory failure Cardiovascular failure CNS failure R2  0.002  0.023   0.001   0.002 R2 = regression coefficient of determination !!Table 2. Blood glucose vs. outcomes Outcome Caloric intake Number of infections Ventilator days ICU LOS Hospital LOS R2  0.018  0.022   0.010  0.021  0.006 R2 = regression coefficient of determination !!!1Conclusions: Blood glucose concentrations were not associated with organ failure, ventilator days, number of infections, ICU LOS, or hospital LOS in critically ill trauma patients receiving EN. In addition, blood glucose concentrations were not affected by the amount of calories administered to trauma patients while in the ICU.!2

Blood glucose concentration does not correlate with organ failure or outcome in trauma patients receiving enteral nutrition

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Blood glucose concentration does not correlate with organ failure or outcome in trauma patients receiving enteral nutrition

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