The final publication is available at Springer via http://dx.doi.org/10.1007/s00521-011-0672-9A framework of fully integrated hybrid systems (HSs) is proposed for the development and management of HS which involve databases, advanced user interfaces, symbolic systems, and artificial neural networks. This framework provides a common input–output interface among those HS modules developed on the framework, with a completely two-directional flow control and a highly parallel processing. This integration framework facilitates the incorporation of heterogeneous modules, together with their subsequent management and updating
