Knowledge management, competitive intelligence, data mining are all buzzwords in a more digital and complex world. Nowadays, digital information and IT-based knowledge creation and application are present in most successful business initiatives. Unveil the surrounding factors of these successes is critical and therefore, this article discusses the relationship of digital patterns to knowledge management creation and application. It argues that some of the enablers and inhibitors come from firms’ regional and/or local environment. Understanding the factors that determine technology and knowledge management adoption is thus a highly relevant topic from the policy point of view. Considering the growing impact of e-business on regions, this research sets the background for the assessment of the relationship among ICT, knowledge management, and e-business practices
