The aim of the present study was primarily to evaluate the medicinal uses of the plants known to some western Kordofan tribes and to encourage preservation of their culture, conservation and sustainable utilization of the plant wealth. The present study revealed a record of 49 plant species belonging to 26 families which are used in the folk medicine of West Kordofan, Sudan. It is believed to be a form of healthcare in many aspects of curing practices. The plants were arranged alphabetically by their family name followed by species name, local name, parts used, mode of preparation and medicinal uses. This wisdom available with the tribes is transmitted only through oral communication therefore needs conservation