Arendt-Nielsen, Lars

Nguyen, T. T. L.

Phan, Hung Ai

Wang, Kelun

English

    Aalborg UniversitetPain and  discomfort after intraoral injection of epinephrine-containing anestheticsolutionsPhan, Hung Ai; Nguyen, T. T. L.; Arendt-Nielsen, Lars; Wang, KelunPublished in:Journal of Dental ResearchPublication date:2012Document VersionAccepted author manuscript, peer reviewed versionLink to publication from Aalborg UniversityCitation for published version (APA):Phan, H. A., Nguyen, T. T. L., Arendt-Nielsen, L., & Wang, K. (2012). Pain and discomfort after intraoral injectionof epinephrine-containing anesthetic solutions. Journal of Dental Research, 91(Spec.Iss. C), Sess. 5A, No.169789. http://www1.iadr-sea-2012.com.hk/poster_session/iadr-poster-sessions.htmlGeneral rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.            ? Users may download and print one copy of any publication from the public portal for the purpose of private study or research.            ? You may not further distribute the material or use it for any profit-making activity or commercial gain            ? You may freely distribute the URL identifying the publication in the public portal ?Take down policyIf you believe that this document breaches copyright please contact us at vbn@aub.aau.dk providing details, and we will remove access tothe work immediately and investigate your claim.Pain and  discomfort after intraoral injection of epinephrine-containing anesthetic solutions    H.A. Phan*, T.T.L. Nguyen*, Lars Arendt-Nielsen**, Kelun Wang**  (*Faculty of Odonto Stomatology, University of  Medical Sciences - Vietnam,  Ho Chi Minh City, Vietnam **Center for Sensory-Motor Interaction, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Denmark)  Abstract Objectives: The objective of this study was to compare the pain intensity and discomfort produced by 3% mepivacaine plain and 2% lidocaine with 1:100,000 epinephrine  during local anesthesia in the maxilla among Vietnamese youths  Methods: A randomized, double-blinded, placebo- controlled clinical trial was conducted in 107 healthy volunteer dental students (56 males and 51 females ) age between 22-24 at the Faculty of Odonto-Stomatology, HoChiMinh city, Vietnam. Each subject received 2 topical anesthetics (on each buccal mucosa of maxillary central incisors) and then 2 injections using metal syringe. The coded topical application was placebo or topical anesthetic gel (20% Benzocaine gel). The modified needle was a traditional 27-gauge with injection depth of 1.5mm. Allocation to side was randomized; operator, volunteers and outcome assessor were blinded to the identity of the topical anesthetic and the local anesthetic solution . After 5 seconds of needle insertion using bite-rest on-pull injection technique, some drops of anesthetic solution were released. After that, the same procedure was conducted on the rest site. Volunteers recorded injection pain intensity and discomfort on VAS.  The pain categories were clasified basing on the VAS. The Chi Square test was applied.  Results: There were no statistical significant differences in perceived pain and discomfort on injection of 2% lidocaine with 1:100.000 epinephrine or 3% mepivacaine plain (p-value=0.61 with placebo and p-value=0.29 with benzocaine). In addition, the greatest majority of injection had a score of 0 (210/214 injections)  Conclusions: The acidic nature of the drug is not reponsible for the pain caused by the local anesthetic   

Pain and discomfort after intraoral injection of epinephrine-containing anesthetic solutions

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Pain and discomfort after intraoral injection of epinephrine-containing anesthetic solutions

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