Barrett, Christopher

Dornan, Faculty Advisor, Dr. Wayne

Digital Commons @ Illinois Wesleyan University

Illinois Wesleyan UniversityDigital Commons @ IWUJohn Wesley Powell Student ResearchConference 1992, 3rd Annual JWP ConferenceApr 25th, 10:30 AM - 4:30 PMThe Effects of Bilateral Injections of Neurokinin Kinto the Dorsal Midbrain Central Gray on FemaleRat Sexual Behavior: A Pilot StudyChristopher BarrettIllinois Wesleyan UniversityDr. Wayne Dornan, Faculty AdvisorIllinois Wesleyan UniversityFollow this and additional works at: http://digitalcommons.iwu.edu/jwprcThis Event is brought to you for free and open access by The Ames Library, the Andrew W. Mellon Center for Curricular and FacultyDevelopment, the Office of the Provost and the Office of the President. It has been accepted for inclusion in Digital Commons @ IWU bythe faculty at Illinois Wesleyan University. For more information, please contact digitalcommons@iwu.edu.©Copyright is owned by the author of this document.Christopher Barrett and Dr. Wayne Dornan, Faculty Advisor, "The Effects of Bilateral Injections of Neurokinin K into theDorsal Midbrain Central Gray on Female Rat Sexual Behavior: A Pilot Study" (April 25, 1992). John Wesley PowellStudent Research Conference. Paper 54.http://digitalcommons.iwu.edu/jwprc/1992/posters/54THE EFFECTS OF BILATERAL INJECTIONS OF NEUROKININ K INTO THE DORSAL MIDBRAIN CENTRAL GRAY ON FEMALE RAT SEXUAL BEHAVIOR: A PILOT STUDY Christopher Barrett, Department of Psychology, lWU, Dr. Wayne Dornan* The dorsal midbrain central gray (dMCG) an area within the central nervous system, has been implicated in the neural control of sexual receptivity (lordosis behavior) in steroid-primed ovariectomized female rats. Bilateral lesions of the dMCG disrupt lordosis, while electrical stimulation facilitate the display of lordosis behavior in steroid-primed ovariectomized female rats. Additionally, bilateral injections of the neurokinin substance P (sP) � into the dMCG have been reported to facilitate lordosis behavior when compared to injections of saline (controls). Recently, accumulating evidence suggests that neurokinin K (NICK), another product of the sP gene, regulates the expression of male rat copulatory behavior. Bilateral injections of NICK into the preoptic area of male rats has been reported to have an inhibitory effect on the expression of male rat sexual behavior. Therefore, this pilot study assessed what effects NICK will have upon female rat sexual behavior. NICK or saline was injected bilaterally into the dMCG of steroid primed ovariectomized female rats, and the effects of these injections on sexually receptivity was assessed. 

The Effects of Bilateral Injections of Neurokinin K into the Dorsal Midbrain Central Gray on Female Rat Sexual Behavior: A Pilot Study

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The Effects of Bilateral Injections of Neurokinin K into the Dorsal Midbrain Central Gray on Female Rat Sexual Behavior: A Pilot Study

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