We report a case of bronchiolitis obliterans organizing pneumonia (BOOP) caused by minocycline (MINO). A 59- year-old man visited to our hospital because of flu-like symptoms. He had been treated with MINO for a few weeks for the skin eruption. The chest radiograph showed consolidations in both lung fields. He was admitted to our hospital for further examination. An elevation of lymphocyte percentage was seen in his bronchoalveolar lavage and a diagnosis of BOOP was confirmed by video-assisted thoracoscopic lung biopsy. The symptoms, laboratory and radiological findings gradually improved without steroid therapy. Although the lymphocyte stimulation test (LST) of peripheral blood for MINO was negative, a positive oral provocation test confirmed the role of MINO in the induction of BOOP
