A discussion of experimental approaches and theoretical difficulties in the identification of ribozymes with novel catalytic functions

Hammann, Christian

Westhof, Eric

English

PubMed

New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes

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Searching genomes for ribozymes and riboswitches

Searching genomes for ribozymes and riboswitches

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