Background: Dyslipidemia is an abnormal lipid profile in serum, one of which is
the increase level of triglyceride. Red dragon fruit (Hylocereus polyrhizus) has
been proven to repair lipid profile since it contains phenolic and flavonoid. The
red dragon fruit’s peel contains nutrients such as carbohydrate, fat, protein, fiber
and betacyanin compounds.
Objective: To discover the differences between effect of red dragon fruit’s peel
steeping and flesh juice administration on serum triglyceride levels of Sprague
dawley rats with dyslipidemia.
Method: This research is a true experimental research, uses pre and post test with
control group design. 10 weeks-aged male Sprague dawley rats were used as
samples, induced with dyslipidemia by quail eggs and cholic acid. Group K(-) was
given standard meal, group K(+) was given high cholesterol meal, group P1 was
given red dragon fruit peel steeping and group P2 was given flesh juice of red
dragon fruit. Serum triglyceride levels was examined with CHOD-PAP and GPOPAP
method. Data then were being analyzed with paired t test and one-way
ANOVA.
Result: There were significant differences between before and after intervention
on group K(-), K(+), P1 and P2. The administration of peel steeping for 14 days
has proven to decrease triglyceride level by 53,61 mg/dl (SD= 4,06), meanwhile
flesh juice of red dragon fruit has proven to decrease triglyceride level by 36,99
mg/dl (SD= 8,14). After intervention there were differences in triglyceride levels
mean value between the groups p=0,000 except for K(-) with P1 (peel steeping)
p=1.000.
Conclusion: The administration of red dragon fruit’s peel steeping and flesh juice
for 14 days with dose of 9,08 g/200 gBW rat and 1,53 g/200 gBW rat were able to
decrease serum triglyceride levels each by 53,61 mg/dl (SD= 4,06) and 36,99
mg/dl (SD=8,14) on dyslipidemia Sprague dawley rats.
Keywords: red dragon fruit peel steeping, flesh juice of red dragon fruit, serum
triglyceride, dyslipidemi
