Population synchronization exists ubiquitously in ecological systems, of which the underlying causes and the roles in species extinction remain a perplexing puzzle. It is generally believed that the coherence of population dynamics is detrimental and regarded as a major cause of global extinction. A central but unsolved question in ecology of great importance for conservation and biological control is how to destroy the pernicious coherent structures. Here, a top-down approach is adopted to tackle the challenge. A feedback strategy accordingly is applied to stabilize the metacommunity, i.e., to reduce excessive metapopulation fluctuations by means of introducing or removing a planned number of individuals. As a result, the feedback desynchronizes correlated population oscillations, giving rise to either complex asynchronous traveling waves or "amplitude death"; cessation of all individual population cycles. Together with the construction of corridors, my method may provide an efficient way to protect those species threatened as a result of, e.g. habitat fragmentation. I anticipate my essay provides a general mechanism against widespread harmful synchronization in physical and biological systems, for example, for developing a "brain anti-pacemaker" for neurological diseases such as Parkinson's disease and epilepsy closely linked to pathologically synchronized neuronal discharges
